Arama Sonuçları

Listeleniyor 1 - 3 / 3
  • Yayın
    Convolutional attention network for MRI-based Alzheimer's disease classification and its interpretability analysis
    (IEEE, 2021-09-17) Türkan, Yasemin; Tek, Faik Boray
    Neuroimaging techniques, such as Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET), help to identify Alzheimer's disease (AD). These techniques generate large-scale, high-dimensional, multimodal neuroimaging data, which is time-consuming and difficult to interpret and classify. Therefore, interest in deep learning approaches for the classification of 3D structural MRI brain scans has grown rapidly. In this research study, we improved the 3D VGG model proposed by Korolev et al. [2]. We increased the filters in the 3D convolutional layers and then added an attention mechanism for better classification. We compared the performance of the proposed approaches for the classification of Alzheimer's disease versus mild cognitive impairments and normal cohorts on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. We observed that both the accuracy and area under curve results improved with the proposed models. However, deep neural networks are black boxes that produce predictions that require further explanation for medical usage. We compared the 3D-data interpretation capabilities of the proposed models using four different interpretability methods: Occlusion, 3D Ultrametric Contour Map, 3D Gradient-Weighted Class Activation Mapping, and SHapley Additive explanations (SHAP). We observed that explanation results differed in different network models and data classes.
  • Yayın
    An adaptive locally connected neuron model: Focusing neuron
    (Elsevier B.V., 2021-01-02) Tek, Faik Boray
    This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The experiments include tests of focusing neuron networks of one or two hidden layers on synthetic and well-known image recognition data sets. The results demonstrated that the focusing neurons can move their receptive fields towards more informative inputs. In the simple two-hidden layer networks, the focusing layers outperformed the dense layers in the classification of the 2D spatial data sets. Moreover, the focusing networks performed better than the dense networks even when 70% of the weights were pruned. The tests on convolutional networks revealed that using focusing layers instead of dense layers for the classification of convolutional features may work better in some data sets.
  • Yayın
    Retinal disease classification from bimodal OCT and OCTA using a CNN-ViT hybrid architecture
    (Institute of Electrical and Electronics Engineers Inc., 2025-09-21) Aydın, Ömer Faruk; Tek, Faik Boray; Turkan, Yasemin
    Retinal diseases are the leading cause of vision impairment and blindness worldwide. Early and accurate diagnosis is critical for effective treatment, and recent advances in imaging technologies such as Optical Coherence Tomography (OCT) and OCT Angiography (OCTA), have enabled detailed visualization of the retinal structure and vasculature. By leveraging these modalities, this study proposes an advanced deep learning architecture called MultiModalNet for automated multi-class retinal disease classification. MultiModalNet employs a dual-branch design, where OCTA projection maps are processed through a ResNet101 encoder, and cross-sectional slices from the OCT volume (B-scans) are analyzed using a Vision Transformer (ViT-Large). The extracted features from both branches were fused and passed through the fully connected layers for the final classification. Evaluated on the 3-class OCTA-500 dataset, which includes Age-related Macular Degeneration (AMD), Diabetic Retinopathy (DR), and Normal cases, the proposed model achieved state-of-the-art classification accuracy of 94.59 percent, significantly o utperforming single-modality baselines. This result highlights the effectiveness of integrating vascular and structural information to improve the diagnostic performance. The findings suggest that hybrid multi-modal deep learning approaches can play a transformative role in computer-aided ophthalmology, enhancing both clinical decision-making and screening workflows.