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  • Yayın
    Integrated ultrasonic imaging systems based on CMUT arrays: Recent progress
    (IEEE, 2004) Wygant, Ira O.; Zhuang, Xuefeng; Yeh, David T.; Nikoozadeh, Amin; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus Thomas
    This paper describes the development of an ultrasonic imaging system based on a two-dimensional capacitive micromachined ultrasonic transducer (CMUT) array. The transducer array and front-end electronics are designed to fit in a 5-mm endoscopic channel. A custom-designed integrated circuit, which comprises the front-end electronics, will be connected with the transducer elements via through-wafer interconnects and flip-chip bonding. FPGA-based signal-processing hardware will provide real-time three-dimensional imaging. The imaging system is being developed to demonstrate a means of integrating the front-end electronics with the transducer array and to provide a clinically useful technology. Integration of the electronics can improve signal-to-noise ratio, reduce the number of cables connecting the imaging probe to a separate processing unit, and provide a means of connecting electronics to large two-dimensional transducer arrays. This paper describes the imaging system architecture and the progress we have made on implementing each of its components: a 16×16 CMUT array, custom-designed integrated circuits, a flip-chip bonding technique, and signal-processing hardware.
  • Yayın
    An endoscopie imaging system based on a two-dimensional CMUT array: real-time imaging results
    (IEEE, 2005) Wygant, Ira O.; Zhuang, Xuefeng; Yeh, David T.; Vaithilingam, Srikant; Nikoozadeh, Amin; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus Thomas
    Real-time catheter-based ultrasound imaging tools are needed for diagnosis and image-guided procedures. The continued development of these tools is partially limited by the difficulty of fabricating two-dimensional array geometries of piezoelectric transducers. Using capacitive micromachined ultrasonic transducer (CMUT) technology, transducer arrays with widely varying geometries, high frequencies, and wide bandwidths can be fabricated. A volumetric ultrasound imaging system based on a two-dimensional, 16×l6-element, CMUT array is presented. Transducer arrays with operating frequencies ranging from 3 MHz to 7.5 MHz were fabricated for this system. The transducer array including DC bias pads measures 4 mm by 4.7 mm. The transducer elements are connected to flip-chip bond pads on the array back side with 400-?m long through-wafer interconnects. The array is flip-chip bonded to a custom-designed integrated circuit (IC) that comprises the front-end electronics. Integrating the front-end electronics with the transducer array reduces the effects of cable capacitance on the transducer's performance and provides a compact means of connecting to the transducer elements. The front-end IC provides a 27-V pulser and 10-MHz bandwidth amplifier for each element of the array. An FPGA-based data acquisition system is used for control and data acquisition. Output pressure of 230 kPa was measured for the integrated device. A receive sensitivity of 125 mV/kPa was measured at the output of the amplifier. Amplifier output noise at 5 Mhz is 112 nV/?Hz. Volumetric images of a wire phantom and vessel phantom are presented. Volumetric data for a wire phantom was acquired in real-time at 30 frames per second.
  • Yayın
    A miniature real-time volumetric ultrasound imaging system
    (SPIE-Int Soc Optical Engineering, 2005) Wygant, Ira O.; Yeh, David T.; Zhuang, Xuefeng; Nikoozadeh, Amin; Oralkan, Ömer; Ergün, Arif Sanlı; Karaman, Mustafa; Khuri-Yakub, Butrus Thomas
    Progress made in the development of a miniature real-time volumetric ultrasound imaging system is presented. This system is targeted for use in a 5-mm endoscopic channel and will provide real-time, 30-mm deep, volumetric images. It is being developed as a clinically useful device, to demonstrate a means of integrating the front-end electronics with the transducer array, and to demonstrate the advantages of the capacitive micromachined ultrasonic transducer (CMUT) technology for medical imaging. Presented here is the progress made towards the initial implementation of this system, which is based on a two-dimensional, 16×16 CMUT array. Each CMUT element is 250 µm by 250 µm and has a 5-MHz center frequency. The elements are connected to bond pads on the back side of the array with 400-µm long through-wafer interconnects. The transducer array is flip-chip bonded to a custom-designed integrated circuit that comprises the front-end electronics. The result is that each transducer element is connected to a dedicated pulser and low-noise preamplifier. The pulser generates 25-V, 100-ns wide, unipolar pulses. The preamplifier has an approximate transimpedance gain of 500 k? and 3-dB bandwidth of 10 MHz. In the first implementation of the system, one element at a time can be selected for transmit and receive and thus synthetic aperture images can be generated. In future implementations, 16 channels will be active at a given time. These channels will connect to an FPGA-based data acquisition system for real-time image reconstruction.
  • Yayın
    Beamforming and hardware design for a multichannel front-end integrated circuit for real-time 3D catheter-based ultrasonic imaging
    (SPIE-Int Soc Optical Engineering, 2006) Wygant, Ira O.; Karaman, Mustafa; Oralkan, Ömer; Khuri-Yakub, Butrus Thomas
    We are working on integrating front-end electronics with the ultrasound transducer array for real-time 3D ultrasound imaging systems. We achieve this integration by flip-chip bonding a two-dimensional transducer array to an integrated circuit (IC) that comprises the front-end electronics. The front-end IC includes preamplifiers, multiplexers, and pulsers. We recently demonstrated a catheter-based real-time ultrasound imaging system based on a 16 x 16-element capacitive micromachined ultrasonic transducer (CMUT) array. The CMUT array is flip-chip bonded to a front-end IC that includes a pulser and preamplifier for each element of the array. To simplify the back-end processing and signal routing on the IC for this initial implementation, only a single array element is active at a time (classic synthetic aperture (CSA) imaging). Compared with classic phased array imaging (CPA), where multiple elements are used on transmit and receive, CSA imaging has reduced signal-to-noise ratio and prominent grating lobes. In this work, we evaluate three array designs for the next generation front-end IC. The designs assume there are 16 receive channels and that numerous transmit pulsers are provided by the IC. The designs presented are: plus-transmit x-receive, boundary-transmit x-receive with no common elements, and full-transmit x-receive with no common elements. Each design is compared with CSA and CPA imaging. We choose to implement an IC for the full-transmit x-receive with no common elements (FT-XR-NC) design for our next-generation catheter-based imaging system.