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Yayın The effect of the interaction between autistic traits and psychotic proneness on empathy: a cross-sectional study with a non-clinical sample(Emerald Publishing, 2023-11-08) Yıldırım, ElifPurpose: Recent evidence indicates an improving effect of the co-occurrence of autistic traits and psychotic symptoms on social cognition, but there is no agreement on the effect of the interaction between autistic traits and psychotic proneness on empathy. The aim of this study is to examine the effect of the interaction between autistic traits and positive psychotic experiences on cognitive and affective empathy. Design/methodology/approach: The sample consisted of 420 adults aged between 18 and 60. Assessments were administered anonymously online. Empathic abilities were evaluated by the Interpersonal Reactivity Index (IRI). While Autism Spectrum Quotient (AQ) was applied to measure autistic traits, The Community Assessment of Psychic Experience (CAPE) was used as a measurement of positive psychotic experiences. Findings: A series of regression analyses showed that although AQ and CAPE scores were not correlated with cognitive-IRI, the interaction between these scores predicted cognitive-IRI scores. It was found that the personal distress subscale of IRI was significantly associated with AQ, but this relationship was moderated by CAPE scores. Originality/value: These findings provide a different perspective on understanding social cognitive impairments in autism, which may have potential clinical implications. Findings also contribute to explaining the individual differences in empathic abilities.Yayın Shrinkage of olfactory amygdala connotes cognitive impairment in patients with Parkinson’s disease(Springer, 2023-10) Ay, Ulaş; Yıldırım, Zerrin; Erdoğdu, Emel; Kıçik, Ani; Öztürk Işık, Esin; Demiralp, Tamer; Gürvit, HakanDuring the caudo-rostral progression of Lewy pathology, the amygdala is involved relatively early in Parkinson’s disease (PD). However, lesser is known about the volumetric differences at the amygdala subdivisions, although the evidence mainly implicates the olfactory amygdala. We aimed to investigate the volumetric differences between the amygdala’s nuclear and sectoral subdivisions in the PD cognitive impairment continuum compared to healthy controls (HC). The volumes of nine nuclei of the amygdala were estimated with FreeSurfer (nuclear parcellation-NP) from T1-weighted images of PD patients with normal cognition (PD-CN), PD with mild cognitive impairment (PD-MCI), PD with dementia (PD-D), and HC. The appropriate nuclei were then merged to obtain three sectors of the amygdala (sectoral parcellation-SP). The nuclear and sectoral volumes were compared among the four groups and between the hyposmic and normosmic PD patients. There was a significant difference in the total amygdala volume among the four groups. In terms of nuclei, the bilateral cortico-amygdaloid transition area (CAT) and sectors superficial cortex-like region (sCLR) volumes of PD-MCI and PD-D were less than those of the PD-CN and HC. A linear discriminant analysis revealed that left CAT and left sCLR volumes classified the PD-CN and cognitively impaired PD (PD-CI: PD-MCI plus PD-D) with 90.7% accuracy according to NP and 85.2% accuracy to SP. Similarly, left CAT and sCLR volumes correctly identified the hyposmic and normosmic PD with 64.8% and 61.1% accuracies. Notably, the left olfactory amygdala volume successfully discriminated cognitive impairment in PD and could be used as neuroimaging-based support for PD-CI diagnosis.Yayın Evaluation of post-swallow residue with visual analysis of swallowing efficiency and safety in patients with idiopathic Parkinson's disease(Sage Publications Inc, 2023-12) Doruk, Can; Çaytemel, Berkay; Şahin, Erdi; Kara, Hakan; Samancı, Bedia; Abay, Sevinç Nisa; Bilgiç, Başar; Hanağası, Haşmet; Başaran, Bora; Enver, Necati; Rameau, AnaisObjectives: Dysphagia is common in idiopathic Parkinson's disease (IPD) and is associated with impairments in both swallowing safety and swallowing efficiency. The goals of this study were to define post-swallow residue patterns in people with IPD and describe pathophysiological endoscopic findings affecting residue accumulation. Methods: This was a prospective single-blinded cross-sectional cohort study of patients with the diagnosis of IPD recruited from a Movement Disorder Clinic. Clinical variables included patient age, cognitive function, and measures of disease severity, and laryngoscopic examinations with a flexible endoscopic evaluation of swallowing (FEES) were completed for each patient. Visual Analysis of Swallowing Efficiency and Safety (VASES) was used to analyze FEES. Post-swallow residue outcomes and non-residue endoscopic outcomes including the Bowing index, Penetration Aspiration Scale (PAS) score, premature leakage, and build-up phenomenon were evaluated. Multiple regression models were used to evaluate factors affecting the residue at different anatomic levels. Results: Overall 53 patients completed the study. The multiple regression analyses showed a relation between (1) the presence of residue at the level of oropharynx and epiglottis with premature leakage, (2) the presence of residue at the level of the laryngeal vestibule and vocal folds with build-up phenomenon, and (3) the presence of residue at the level of the hypopharynx, laryngeal vestibule, and subglottis with airway invasion. Conclusion: Residue pattern during FEES is associated with specific swallow dysfunctions in IPD. Using residue localization and quantification may be a helpful tool in assessing the impact of targeted swallowing interventions in patients with IPD and dysphagia.Yayın Turkish validity and reliability study of the childhood illness attitude scale(Routledge, 2025-03) Aktan, Zekeriya Deniz; İnci İzmir, Sevim Berrin; Ünlü, Beyza; Yılmaz Kahraman, İpek SuSevere forms of health anxiety cause serious dysfunction in people’s lives. Childhood Illness Attitude Scales (CIAS) is an assessment tool used to evaluate childhood health anxiety yet has not been validated for use in Turkey. The study aimed to examine the psychometric properties and factor structure of the Turkish version of the CIAS (CIAS-TR). The scale was administered to 306 children aged between 8 and 15 years. In addition to the CIAS-TR, participants were asked to complete the Screen for Child Anxiety-Related Emotional Disorders (SCARED) and the Pediatric Quality of Life Inventory (PedsQL). To measure test-retest reliability, CIAS-TR was completed by participants 15 days later. Results demonstrated good psychometric properties with high internal consistency and test-retest reliability. A positive correlation with SCARED and a negative correlation with PedsQL. Results from Confirmatory Factor Analysis suggested that a four-factor model best fit the data. The findings of the study indicate that the Turkish adaptation of the CIAS is an appropriate tool for assessing health anxiety in children.Yayın Uzaktan nöropsikolojik değerlendirme: telenöropsikoloji(BAYT Yayıncılık, 2024-05-25) Yıldırım, Elif; Soncu Büyükişcan, Ezgi; Akça Kalem, Şükriye; Gürvit, İ. HakanAmaç: Nöropsikolojik testlerin hastalara uzaktan, telefon ve videokonferans aracılığı ile yapılan uygulamalarını içeren telenöropsikoloji, uzakta yaşayan ya da hareket kısıtlılığı bulunan hastaların sağlık hizmetlerine ulaşım imkânını genişletebilmektedir. Covid-19 pandemisinin ortaya çıkması ile kognitif değerlendirmelerde telenöropsikoloji kullanımı önemli bir artış göstermiştir. Bu derlemede telenöropsikoloji ile ilgili yapılan çalışmaların sonuçlarının ve telenöropsikolojik değerlendirme ile ilgili temel esasların eleştirel bir şekilde gözden geçirilmesi amaçlanmıştır. Buna ek olarak, bu derlemede Türkiye uygulamaları için geliştirilmiş “ev temelli telenöropsikoloji uygulama rehberi” genel hatları ile paylaşılmıştır. Yöntem: Web of Science ve Pubmed veri tabanları kullanılarak konu ile ilgili erişilebilen tüm makale türlerini kapsayan bir şekilde literatür taraması yapılmıştır. Bulgular: Klinik temelli ve ev temelli telenöropsikolojik değerlendirme ile ilgili çalışmaların sonuçları dikkat, bellek, yürütücü işlevler ve dil gibi kognitif işlevleri değerlendiren ve özellikle sözel uygulamaya dayanan nöropsikolojik testlerin telenöropsikolojik değerlendirmede güvenilir bir şekilde uygulanabileceğini göstermektedir. Fakat telenöropsikolojik değerlendirmeye alınacak hastaların yönlendirilmesinde, değerlendirmede kullanılacak testlerin seçiminde ve etik konularda dikkat edilmesi gereken unsurlar bulunmaktadır. Buna ek olarak, telenöropsikolojik değerlendirmenin etkili bir şekilde yürütülmesi için görüşme öncesinde ve sırasında hem klinisyenin hem de hasta ve/veya hasta yakınının uygulanması önerilen adımların takip edilmesi önemlidir. Sonuç: Her ne kadar klinik nöropsikoloji pratiğinde hasta ile doğrudan temas kurmak önemli bir unsur olsa da gerekli durumlarda ve yetkin uzmanlar tarafından uygun uygulama prosedürleri takip edilerek yapılan telenöropsikolojik değerlendirmeler yüz yüze değerlendirmeler için iyi bir alternatif olabilir.Yayın The comparison of functional connectivity in Parkinson’s Disease patients with and without Parkin gene mutations(Turkish Neuropsychiatric Society, 2025-06-19) Çebi, Merve; Ay, Ulaş; Kıçik, Ani; Erdoğdu, Emel; Tepgeç, Fatih; Uyguner, Zehra Oya; Tüfekçioğlu, Zeynep; Samancı, Bedia; Bilgiç, Başar; Emre, Murat; Demiralp, Tamer; Hanağası, Haşmet AyhanIntroduction: Mapping the functional connectivity of brain regions became appealing in recent research in neurology. Accordingly, a growing body of evidence shows resting-state functional connectivity (rsFC) changes in neurodegenerative disorders including Parkinson’s Disease (PD). As characterised by extensive and progressive dopaminergic loss in the substantia nigra, PD emerges with serious motor and non-motor dysfunctions. In the literature, the minority of PD cases have been associated with certain genetic mutations. The aim of this study was to investigate the rsFC in a group of PD patients having Parkin gene mutation. Method: Twelve PD patients with Parkin mutation (PP-PD), 12 PD patients without Parkin mutation (PN-PD) and 12 healthy controls (HC) were included in the study. All participants underwent a resting-state functional magnetic resonance imaging as well as a neuropsychological assessment and clinical examination. Results: Results indicated that PP-PD had longer disease duration, a higher rate of dyskinesia and lower scores on complex visual perception tests. The resting state networks showed that all PD (consisting of PP-PD and PN-PD) and PP-PD groups had increased functional connectivity in the frontoparietal network as compared to the HC. In addition, the PP-PD group displayed decreased functional connectivity in the dorsal attention network compared to the PN-PD. Conclusion: In conclusion, our data suggests that PD with Parkin gene mutation might be emerging with distinct resting state functional connectivity changes in the brain.Yayın Decision making, emotion recognition and childhood traumatic experiences in murder convicts ımprisoned with aggravated life sentence: a prison study(Turkish Neuropsychiatric Society, 2025-03) Çıkrıkçılı, Uğur; Yıldırım, Elif; Buker, Seda; Ger, Can; Erözden, Ozan; Gürvit, Hakan; Saydam, BilginIntroduction: Decision-making and emotion recognition are two fundamental themes in social cognition. Disorders in these areas can lead to interpersonal, psychosocial, and legal problems for the individual and society. The likelihood of consequent aggression and crime makes them foci of forensic psychiatry over time. In this study, two developmental disorders that have a clear relationship with crime, that are antisocial personality disorder (ASPD), and psychopathy are investigated for their relationship with these social cognitive deficits.Methods: The present study involved 23 male prison inmates who were diagnosed with both antisocial personality disorder and psychopathy, as well as 23 control participants who were matched for age, gender, and level of education. Following the psychiatric interview, Reading the Mind in the Eyes Test (RMET), the Iowa Gambling Test (IGT), Toronto Alexithymia Scale (TAS), Defense Styles Questionnaire (DSQ), Childhood Psychic Trauma Scale (CTQ), Hare Psychopathy Checklist (PCL-R) were administered to all participants. Results: The results of the study showed that ASPD group performed statistically worse than healthy controls in TAS, CTQ, all items of DSQ, PCL-R Factor 1 and 2, and all the IGT scores (p<0.05). There were no statistically significant difference between in the RMET test performancesConclusion: These results suggest that ASPD and psychopathy lead to impaired decision-making behaviors due to the inability to recognize one’s own emotions and impulsivity, and that these characteristics play a critical role in the criminal behavior of individuals. In addition, contrary to expectations, the results of affective theory of mind assessed with the RMET showed similar characteristics in homicide convicts and healthy controls. These data indicate the need for further research in the field of forensic psychiatry.Yayın Understanding the development of eye movement desensitization and reprocessing therapy for children: findings from a bibliometric study(Springer Publishing Co., 2025-05-20) Çitil Akyol, Canan; İnci İzmir, Sevim BerrinBibliometric analysis is a quantitative method used to determine the development of a specific academic field, publication trends, the most influential authors, and key topics. Systematically analyzing research on the use of eye movement desensitization and reprocessing (EMDR) in children and adolescents is important for identifying the prominent themes in this area and revealing future research needs. Therefore, this study aims to systematically examine the academic development in this field by taking a bibliometric perspective on the existing literature regarding EMDR applications in children and adolescents. This study examines academic works in the fields of EMDR and child-adolescent mental health conducted between 1998 and 2024 by scanning for the keywords "EMDR", "children", and "child" using a bibliometric analysis approach. A total of 358 papers were found in the Scopus database and published between 1998 and early 2024, and only 223 of them were included in the analysis. The most cited authors, journals, organizations, countries, citation trends, key topics, and current growth were analyzed. The findings indicate that EMDR and child research are experiencing robust scientific growth and are receiving increasingly broader academic and clinical attention.
