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Yayın Machine learning-based model categorization using textual and structural features(Springer Science and Business Media Deutschland GmbH, 2022-09-08) Khalilipour, Alireza; Bozyiğit, Fatma; Utku, Can; Challenger, MoharramModel Driven Engineering (MDE), where models are the core elements in the entire life cycle from the specification to maintenance phases, is one of the promising techniques to provide abstraction and automation. However, model management is another challenging issue due to the increasing number of models, their size, and their structural complexity. So that the available models should be organized by modelers to be reused and overcome the development of the new and more complex models with less cost and effort. In this direction, many studies are conducted to categorize models automatically. However, most of the studies focus either on the textual data or structural information in the intelligent model management, leading to less precision in the model management activities. Therefore, we utilized a model classification using baseline machine learning approaches on a dataset including 555 Ecore metamodels through hybrid feature vectors including both textual and structural information. In the proposed approach, first, the textual information of each model has been summarized in its elements through text processing as well as the ontology of synonyms within a specific domain. Then, the performances of machine learning classifiers were observed on two different variants of the datasets. The first variant includes only textual features (represented both in TF-IDF and word2vec representations), whereas the second variant consists of the determined structural features and textual features. It was finally concluded that each experimented machine learning algorithm gave more successful prediction performance on the variant containing structural features. The presented model yields promising results for the model classification task with a classification accuracy of 89.16%.Yayın Retinal disease classification from bimodal OCT and OCTA using a CNN-ViT hybrid architecture(Institute of Electrical and Electronics Engineers Inc., 2025-09-21) Aydın, Ömer Faruk; Tek, Faik Boray; Turkan, YaseminRetinal diseases are the leading cause of vision impairment and blindness worldwide. Early and accurate diagnosis is critical for effective treatment, and recent advances in imaging technologies such as Optical Coherence Tomography (OCT) and OCT Angiography (OCTA), have enabled detailed visualization of the retinal structure and vasculature. By leveraging these modalities, this study proposes an advanced deep learning architecture called MultiModalNet for automated multi-class retinal disease classification. MultiModalNet employs a dual-branch design, where OCTA projection maps are processed through a ResNet101 encoder, and cross-sectional slices from the OCT volume (B-scans) are analyzed using a Vision Transformer (ViT-Large). The extracted features from both branches were fused and passed through the fully connected layers for the final classification. Evaluated on the 3-class OCTA-500 dataset, which includes Age-related Macular Degeneration (AMD), Diabetic Retinopathy (DR), and Normal cases, the proposed model achieved state-of-the-art classification accuracy of 94.59 percent, significantly o utperforming single-modality baselines. This result highlights the effectiveness of integrating vascular and structural information to improve the diagnostic performance. The findings suggest that hybrid multi-modal deep learning approaches can play a transformative role in computer-aided ophthalmology, enhancing both clinical decision-making and screening workflows.Yayın Self-supervised learning of 3D structure from 2D OCT slices for retinal disease diagnosis on UK biobank scans(Institute of Electrical and Electronics Engineers Inc., 2025-09-21) Nazlı, Muhammet Serdar; Turkan, Yasemin; Tek, Faik BorayThis study presents a self-supervised learning framework for retinal disease classification using Optical Coherence Tomography (OCT) scans. To balance the contextual richness of 3D volumes with the computational efficiency of 2D architectures, we introduce a quasi-3D input generation strategy. Each input is constructed by stacking three OCT slices, sampled from channel-specific Gaussian distributions centered on the volume midplane, and arranged in a standard three-channel 2D format compatible with existing pre-trained models. These quasi-3D images are used to pre-train a Vision Transformer (ViT-Base) via a Masked Autoencoder (MAE) with a shared masking pattern, encouraging the model to reconstruct masked regions by encoding anatomical continuity across slices. Pre-training is conducted on 10,000 unlabeled OCT volumes from the UK Biobank. The encoder is then fine-tuned on the OCTA-500 dataset for three-class and four-class retinal disease classification tasks, including macular degeneration and diabetic retinopathy. The model achieves 92.57% accuracy on the three-class task, matching the performance of RETFound while using over 150 times less pre-training data and a smaller backbone.
