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Yayın Neuropsychiatric outcomes and caregiver distress in primary progressive aphasia(Wiley, 2023-01) Seçkin, Mustafa; Yıldırım, Elif; Demir, İlayda; Orhun, Ömer; Bülbül, Ezgi; Velioğlu, H. Aziz; Öget, Öktem; Yeşilot, Nilüfer; Çoban, Oğuzhan; Gürvit, HakanBackground: In this study, we aimed to outline the neuropsychiatric consequences of primary progressive aphasia (PPA) and to understand how neuropsychiatric symptomatology affects distress in caregivers. Methods: The Neuropsychiatric Inventory (NPI) including the distress index (NPI-Distress) was used. Additional information about the caregiver burden was obtained using Zarit Burden Interview (ZBI). NPI, NPI-Distress, and ZBI data from 17 patients with a clinical diagnosis of PPA were compared with 10 stroke aphasia patients. Neuropsychiatric symptomatology was investigated based on three clusters; Mood, Frontal/Comportmental, and Psychotic/Disruptive. Additionally, the Activities of Daily Living Questionnaire (ADLQ) was used to outline the functional impairment. Twelve healthy controls were included to compare the neurocognitive test scores with PPA and stroke aphasia groups. Results: A greater number of neuropsychiatric symptoms were observed in the PPA group compared to the stroke aphasia group. The number of symptoms in Mood, and Frontal/Comportmental clusters were greater than the number of symptoms in Psychotic/Disruptive clusters in the PPA group, whereas no significant relationship between the number of symptoms and symptom clusters was found in the stroke aphasia group. In the PPA group, a strong correlation was found between the NPI-Frequency × Severity scores and the NPI-Distress scores. Moreover, the NPI-Distress scores in the PPA group strongly correlated with the ZBI scores. Scores for anxiety, irritability/lability, and apathy had a stronger correlation with the NPI-Distress scores compared to the other NPI symptoms. The Communication subscale was the most impaired domain in the PPA group. Travel, and Employment and Recreation subscales showed greater functional impairment in the stroke aphasia group compared to the PPA group. Conclusions: Neuropsychiatric symptoms in PPA in our study were more frequent than previously reported. Furthermore, the distress index of the NPI was not only correlated with the severity of the neuropsychiatric symptoms but also reflected the overall burden on the caregivers in the PPA group.Yayın İfade tanıma için yüz anatomisine dayalı öznitelikler(IEEE, 2014-04-23) Benli, Kristin Surpuhi; Eskil, Mustafa TanerBu çalışmada yüz ifadesi tanıma için kas kuvvetlerine dayalı yeni öznitelikler öneriyoruz. Yüz üzerinde seçtiğimiz noktaların video üzerindeki hareketlerini izleyerek kas kuvvetlerini çözüyoruz. Yüz noktaları, ilk video çerçevesi üzerinde, kas kuvvet alanları üzerinde ilklendirilir. Bu noktalar optik akış algoritması ile izlenir. Noktaların devinimleri yüzün 3 boyutlu yönelimi ve yüz ifadesine dayalı bağıl devinimleri kestirmek için kullanılır. İnsan yüzünü yaylarla, artık-belirtilmiş doğrusal bir denklem sistemi olarak modelliyoruz. Bu sistemi yüz anatomisi kısıtı altında, kas kuvvetleri için çözüyoruz. Ardışık ileri seçim yaparak, temel yüz ifadeleri için en betimleyici kas kümesini belirliyoruz.Yayın An observation based muscle model for simulation of facial expressions(Elsevier Science BV, 2018-05) Erkoç, Tuğba; Ağdoğan, Didem; Eskil, Mustafa TanerThis study presents a novel facial muscle model for coding of facial expressions. We derive this model from unintrusive observation of human subjects in the progress of the surprise expression. We use a generic and single-layered face model which embeds major muscles of the human face. This model is customized onto the human subject's face on the first frame of the video. The last frame of the video is used to project a set of manually marked feature points to estimate the 3 dimensional displacements of vertices due to facial expression. Vertex displacements are used in a mass spring model to estimate the external forces, i.e. the muscle forces on the skin. We observed that the distribution of muscle forces resemble sigmoid or hyperbolic tangent functions. We chose hyperbolic tangent function as our base model and parameterized it using least squares. We compared the proposed muscle model with frequently used models in the literature.
