Methylphenidate significantly improves neurocognitive impairments in children with ADHD
Yükleniyor...
Dosyalar
Tarih
2022-03-06
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This study aimed to investigate the effects of methylphenidate (MPH) on scores on a neurocognitive test battery for individuals with various presentations of attention deficit/hyperactivity disorder (ADHD) and the effect of comorbidities on executive function. This study included 861 children and adolescents aged 7–17 years who were diagnosed with ADHD according to DSM-V criteria. The CNS Vital Signs Battery was utilized to compare the neuropsychological characteristics and MPH treatment responses of patients with predominantly inattentive (ADHD-I) and combined (ADHD-C) presentations of ADHD. Before MPH administration, a statistically significant difference was observed between groups only for complex attention. In addition, the overall prevalence rate of psychiatric comorbidities was 45.5%, and no statistically significant differences were found in the ADHD-I group pre- versus post-MPH administration. Prior to the administration of MPH, statistically significant differences were observed within the ADHD-C group between those with or without comorbidities. However, after MPH administration, these differences between the groups disappeared. The effects of MPH on improving scores on neuropsychological subtests were similar between the groups with different presentations of ADHD. Additionally, MPH treatment was effective despite the presence of comorbidities.
Açıklama
Anahtar Kelimeler
ADHD, Comorbidity, Methylphenidate, Neurocognitive test battery, Presentations of ADHD, Attention-deficit/Hyperactivity disorder, Deficit hyperactivity disorder, Performance-test performance, Response-inhibition, Executive functions, Test battery, Subtypes, Boys, Adolescents
Kaynak
Psychiatry Research
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
311
Sayı
Künye
İnci, S. B., İpçi, M. & Ercan, E. S. (2022). Methylphenidate significantly improves neurocognitive impairments in children with ADHD. Psychiatry Research, 311, 1-8. doi:10.1016/j.psychres.2022.114492
