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Yayın An investigation of affective theory of mind ability and its relation to neuropsychological functions in Alzheimer's disease(John Wiley and Sons Ltd., 2020-09) Yıldırım, Elif; Soncu Büyükişcan, Ezgi; Demirtaş Tatlıdede, Aslı; Bilgiç, Başar; Gürvit, İbrahim HakanAlthough cognitive theory of mind (ToM) has been largely studied within neurodegenerative disorders including Alzheimer's disease (AD), studies focusing on affective ToM are relatively limited, yielding inconsistent findings. The current study aimed at investigating affective ToM abilities within different stages of AD (mild AD dementia [ADD], mild cognitive impairment [MCI], and subjective cognitive impairment [SCI]), together with its relationship with neuropsychological functioning. Eighty-one participants were tested with two different ToM tasks (Faux Pas Recognition Test [FPR] and Reading Mind in the Eyes Test [RMET]) and tests of attention, executive functions, episodic memory, and facial recognition. Our results showed two different affective ToM profiles in AD continuum: while ADD group performed poorly on both tasks of ToM, MCI group displayed deteriorated performance on RMET but not on FPR. In addition, ToM performance was significantly related to episodic memory and verbal fluency within the overall sample. These findings suggest that impairment in the decoding process of emotional cues could begin even in the prodromal stage of AD. In contrast, the reasoning process of emotional information, as measured with FPR, could be preserved until the dementia stage. Moreover, the relation of affective ToM with amnestic functions and verbal abilities could provide evidence of a domain-general ToM impairment in AD.Yayın Assessing the mediating relationships between psychological factors in children with attention deficit hyperactivity disorder and cognitive disengagement syndrome(Routledge Journals, Taylor & Francis Ltd, 2024-04) İnci İzmir, Sevim Berrin; Aktan, Zekeriya Deniz; Ercan, Eyüp SabriThis study aims to investigate the predictive and mediating relationships between emotion dysregulation, internalizing disorders, family functionality, loneliness preference, and executive functions (EF) in children with attention deficit hyperactivity disorder and cognitive disengagement syndrome (ADHD + CDS). This study included 176 children and adolescents (92 boys, 84 girls) who were diagnosed with ADHD + CDS according to the Diagnostic and Statistical Manual of Mental Disorders, the Fifth Edition criteria by a fellowship-trained child and adolescent psychiatrist, between ages 8 -12 (M = 10, SD = 1.52) with a convenience sampling method. The solitude scale for children, difficulties in emotion dysregulation scale, Child Behavior Checklist, Barkley Sluggish Cognitive Tempo Scale, Family assessment device, and CNS Vital Signs test were used. The results showed that difficulty in emotion regulation, preference for loneliness, internalizing disorders and CDS symptom severity did not have a mediating effect between family functionality and EF. Still, emotion dysregulation mediates the relationship between EF and internalizing disorders by itself and through loneliness preference. Also, preference for loneliness and emotion dysregulation had a mediating effect between family functionality and internalizing disorders. Finally, it was found that the effect of emotion regulation difficulty, loneliness preference, and internalizing disorders had a mediating role between CDS symptom severity and family functionality. In conclusion, the information obtained from this study on the etiology of CDS may guide future studies.Yayın Affective theory of mind in human aging: is there any relation with executive functioning?(Routledge, 2019-04) Yıldırım, Elif; Soncu Büyükişcan, Ezgi; Gürvit, İbrahim HakanTheory of Mind (ToM) refers to the ability to make inferences on other’s mental or emotional states. Although there is evidence suggesting that impaired executive functions due to aging could have a negative impact on cognitive ToM, there is still controversy about the effect of age and age-related executive dysfunctions on affective ToM. To investigate affective ToM in healthy aging and its relationship with executive functions, we examined Reading Mind in the Eyes Test (RMET) performance and executive functions among young and older adults. There was no significant difference between age groups regarding their RMET scores. While affective ToM was correlated to executive functioning within the younger group, short term memory was found to be associated with RMET performance among older participants. Furthermore, within the older group, women performed better than men. Our findings suggest a preserved ability of affective ToM in healthy aging, which appears to be independent of executive functioning.Yayın Methylphenidate significantly improves neurocognitive impairments in children with ADHD(Elsevier Ireland Ltd, 2022-03-06) İnci, Sevim Berrin; İpçi, Melis; Ercan, Eyüp SabriThis study aimed to investigate the effects of methylphenidate (MPH) on scores on a neurocognitive test battery for individuals with various presentations of attention deficit/hyperactivity disorder (ADHD) and the effect of comorbidities on executive function. This study included 861 children and adolescents aged 7–17 years who were diagnosed with ADHD according to DSM-V criteria. The CNS Vital Signs Battery was utilized to compare the neuropsychological characteristics and MPH treatment responses of patients with predominantly inattentive (ADHD-I) and combined (ADHD-C) presentations of ADHD. Before MPH administration, a statistically significant difference was observed between groups only for complex attention. In addition, the overall prevalence rate of psychiatric comorbidities was 45.5%, and no statistically significant differences were found in the ADHD-I group pre- versus post-MPH administration. Prior to the administration of MPH, statistically significant differences were observed within the ADHD-C group between those with or without comorbidities. However, after MPH administration, these differences between the groups disappeared. The effects of MPH on improving scores on neuropsychological subtests were similar between the groups with different presentations of ADHD. Additionally, MPH treatment was effective despite the presence of comorbidities.Yayın Cognitive reserve and aging: impacts on theory of mind and executive functions(Routledge, 2025-03) Şandor, Serra; Hıdıroğlu Ongun, Ceren; Yıldırım, ElifAim: This study examines the effects of cognitive reserve (CR) on Executive Functions (EF) and Theory of Mind (ToM). While CR is suggested to mitigate age-related cognitive decline, its relationship with social cognition remains limited and inconsistent in the literature. It was hypothesized that the effect of CR on ToM might be indirect, mediated by EF and working memory. Methods: 225 cognitively healthy participants were included. CR was measured with the Cognitive Reserve Index Questionnaire, EF with verbal fluency and the Stroop Test, and WM using digit span tasks. Structural Equation Modeling was used to analyze the relationships among CR, EF, WM, and SC, controlling for age and gender. Results: CR was significantly associated with both RMET and FPRT performances. Mediation analysis revealed the direct effects of CR on RMET performance, while the effects on FPRT performance were mediated by executive functions. WM had a partial mediating effect on EF and ToM, but did not directly influence FPRT. Education was most strongly associated with RMET performance, while leisure activities were linked to FPRT performance. Conclusion: These findings suggest that CR indirectly supports ToM by enhancing EF and highlight the importance of interventions aimed at strengthening executive control to support social cognition in aging.Yayın Klinik altı otistik özellikler ve psikotik deneyimler ile zihin kuramı arasındaki ilişkide yürütücü işlevlerin rolünün incelenmesi(Işık Üniversitesi, Lisansüstü Eğitim Enstitüsü, 2025-07-01) Erer, Simge Ece; Yıldırım, Elif; Işık Üniversitesi, Lisansüstü Eğitim Enstitüsü, Klinik Psikoloji Yüksek Lisans Programı; Işık University, School of Graduate Studies, Master’s Program in Clinical PsychologySosyal bilişin temel unsurlarından biri olan zihin kuramı, bireylerin diğer insanların duygularını, düşüncelerini ve amaçlarını içeren zihinsel süreçlerini anlama yeteneğini ifade etmektedir. Bu yetenek, bireylerin günlük yaşamda diğer insanlarla sağlıklı ve etkili sosyal ilişkiler kurabilmeleri açısından oldukça önemlidir. Klinik altı otistik özelliklerin ve psikotik deneyimlerin zihin kuramını nasıl etkilediği hakkında çelişkili sonuçlar bulunmaktadır. Bu çalışmanın amacı, klinik altı otistik özellikler ve psikotik deneyimler ile zihin kuramı arasındaki ilişkide yürütücü işlevler ve bilişsel esnekliğin rolünün incelenmesidir. Çalışmaya 18-45 yaş arasında 125 (66 kadın, 59 erkek) katılmıştır. Toplumda Psişik Yaşantıları Değerlendirme Ölçeği (TPYÖ), Otizm Spektrum Anketi (OSA), Sosyal Biliş Film Testi (SBFT), WMS-R Sayı Menzili Alt Testi, Sözel Akıcılık Testi, İz Sürme Testi ve Stroop Testi Çapa Formu ve Bilişsel Esneklik Envanteri ölçüm araçları kullanılmıştır. Araştırmanın sonuçlarına göre, yaş ve eğitim durumu ile zihin kuramı arasında anlamlı bir ilişki vardır. Yetişkinlerde klinik altı otistik özellikler azalmış zihin kuramını yordamaktadır. Otizm Spektrum Bozukluğuna özgü sosyal bilişsel işlevlerdeki belirli bozulmaların bu ilişkiyi açıkladığı düşünülmektedir. Klinik altı psikotik deneyimlerin aşırı zihinselleştirmeyi yordamadığı saptanmıştır. Klinik altı otistik özellikler ile azalmış zihinselleştirme arasındaki ilişkide psikotik deneyimlerin düzenleyici etkisi üzerinde yürütücü işlevlerin ve bilişsel esnekliğin düzenleyici etkisi bulunmamaktadır. Bu bulgular, klinik altı özelliklerin altında yatan bilişsel mekanizmaların ve bu özelliklerin sosyal biliş üzerindeki etkilerinin daha iyi anlaşılmasına katkı sağlamaktadır.Yayın Validation and normative data study for the Turkish version of the movie for the assessment of social cognition (MASC-TR)(Oxford University Press, 2026-02-05) Şandor, Serra; Hıdıroğlu-Ongun, Ceren; Tanfer, Mehmet Can; Gürkaş, Sena; Bora, Emre; Yıldırım, ElifObjective This study aimed to adapt the Movie for the Assessment of Social Cognition (MASC) into Turkish (MASC-TR), examine its psychometric properties, and establish normative data. Additionally, the study investigated the discriminative validity of the MASC-TR in differentiating individuals with autism spectrum disorder (ASD) from healthy controls. Methods The sample comprised 228 healthy adults and 29 individuals with ASD aged 18–45 years. Participants completed the MASC-TR along with established measures of theory of mind (ToM)—the Reading the Mind in the Eyes Test (RMET) and the Faux Pas Recognition Test (FPRT)—as well as non-social cognitive tasks assessing attention, working memory, and executive functions. Reliability analyses included internal consistency and test–retest reliability. Construct validity was assessed via convergent and discriminant correlations. Group comparisons and receiver operating characteristic analyses were used to evaluate discriminative validity, while multifactorial analysis of variance and regression analyses examined demographic effects. Results The MASC-TR demonstrated acceptable internal consistency (α=0.75) and excellent test–retest reliability (ICC=0.98). Significant positive correlations with RMET and FPRT supported convergent validity. Education level emerged as the only significant demographic predictor of MASC-TR performance. The MASC-TR successfully differentiated individuals with ASD from controls (t=−3.87, p<.001), with an optimal cutoff of 23.5 yielding 97% sensitivity and 52% specificity (area under the curve=0.72). Conclusions The findings indicate that the MASC-TR is a valid and reliable measure of social cognition in Turkish adults. The availability of culturally adapted normative data enhances its clinical and research utility for assessing ToM functioning across populations.
