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Yayın Co-array optimization of CMUT arrays for forward-looking IVUS(IEEE, 2009-09) Tekeş, Coşkun; Karaman, Mustafa; Değertekin, Fahrettin LeventThe ring annular array structure is a preferred configuration for implementing Forward-Looking IVUS (FLIVUS) catheters as it allows for volumetric imaging as well as use of a guidewire at the center. CMUT technology is promising for these arrays especially with the flexibility of locating array elements on the circular donut area efficiently. To take advantage of this flexibility, in this study, we introduce a new co-array sampling strategy that improves imaging performance while keeping the number of firings at a level suitable for real-time imaging. The presented co-array sampling strategy is based on the idea of adjusting the element density of the co-array rings in radial direction to suppress side lobes. In non-uniform sampling of the co-array with a given number of firings, the inter-element distances are adjusted both in radial and angular direction from inner ring to outer ring to fit a given apodization function. To test the imaging performance, we performed numerical simulations of the co-array with non-uniform sampling fitting to the raised-cosine apodization. The simulation results shows that sidelobe level can be reduced more than 10 dB by using non-uniform co-array sampling. This approach does use uniform weighting of all Tx and Rx elements in beamforming, and hence does not cause any SNR loss for apodization.Yayın Evaluation of CMUT annular arrays for side-looking IVUS(IEEE, 2009) Şişman, Alper; Zahorian, Jaime S.; Gürün, Gökçe; Karaman, Mustafa; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Hasler, Paul E.Side-looking (SL) IVUS probes are extensively used for management of cardiovascular diseases. Currently SL-IVUS imaging probes use either a single rotating transducer element or solid-state arrays. Probes with single rotating piezoelectric transducer have simple front-end, but have fixed focused operation, and suffers from motion artifacts. Solid-state SL-IVUS imaging probes use piezoelectric transducer arrays and electronic beam-forming. Synthetic phased array processing of signals detected with small-sized elements in these arrays limits the SNR achievable with these probes. In this study, we explore a new SL-IVUS probe architecture employing rotating phased annular CMUT arrays. We tested and compared imaging performance of the existing and proposed probe configurations through simulated point spread functions. We also two fabricated sample annular array designs operating at 20-MHz and 50-MHz. Our experimental measurements on the 20-MHz array in oil shows 105% fractional bandwidth. The 50-MHz array with parylene coating shows approximately 40% fractional bandwidth measured in water. We also present imaging results acquired from wire-targets to test the experimental point-spread functions.Yayın An Analog beamformer for integrated high-frequency medical ultrasound imaging(IEEE, 2011) Gürün, Gökçe; Zahorian, Jaime; Tekeş, Coşkun; Karaman, Mustafa; Hasler, Paul E.; Değertekin, Fahrettin LeventWe designed and fabricated a dynamic receive beamforming integrated circuit (IC) in 0.35-mu m CMOS technology. This beamformer is suitable for integration with an ultrasound annular array for high-frequency (30-50 MHz) intravascular ultrasound (IVUS) imaging. The beamformer IC is capable of buffering, delaying and preamplification for 8 receive channels. We explored an analog delay cell based on a currentmode first-order all-pass filter, which is used as the basic building block to form an analog dynamic delay line. We also explored a bandwidth enhancement method on the delay cell that improved the overall bandwidth of the delay line by a factor of 6. Each delay cell consumes 2.1 mW of power and is capable of generating a tunable delay between 1.75 ns to 2.5 ns, enabling dynamic receive beamforming over a focal range from 1.4 mm to 2 mm. We successfully integrated the fabricated beamformer IC with an 8-element annular array. Our experimental test results demonstrated the desired buffering, preamplification and delaying capabilities of the beamformer.Yayın Dual-annular-ring CMUT array for forward-looking IVUS imaging(IEEE, 2006) Güldiken, Rasim Oytun; Zahorian, Jaime; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Tekeş, Coşkun; Şişman, Alper; Karaman, MustafaWe investigate a dual-annular-ring CMUT array configuration for forward-looking intravascular ultrasound (FL-IVUS) imaging. The array consists of separate, concentric transmit and receive ring arrays built on the same silicon substrate. This configuration has the potential for independent optimization of each array and uses the silicon area more effectively without any particular drawback. We designed and fabricated a 1mm diameter test array which consists of 24 transmit and 32 receive elements. We investigated synthetic phased array beamforming with a non-redundant subset (if transmit-receive element pairs of the dual-annular-ring array. For imaging experiments, we designed and constructed a programmable FPGA-based data acquisition and phased array beamforming system. Pulse-echo measurements along with imaging simulations suggest that dual-ring-annular array should provide performance suitable for real-time FLAVUS applications.Yayın Forward-looking IVUS imaging using a dual-annular ring CMUT array: Experimental results(IEEE, 2007) Güldiken, Rasim Oytun; Zahorian, Jaime S.; Gürün, Gökçe; Qureshi, Muhammad Shakeel; Balantekin, Müjdat; Tekeş, Coşkun; Hasler, Paul E.; Karaman, Mustafa; Carlier, Stephane; Değertekin, Fahrettin LeventThis paper presents the experimental results on forward-looking Intravascular ultrasound (FL-IVUS) using dual-annular-ring CMUT arrays. The array has a diameter of 1mm including bondpads which consists of separate, concentric 24 transmit and 32 receive ring arrays built on the same silicon substrate. This configuration has the potential for Independent optimization of each array and uses the silicon area more effectively without any drawback. For imaging experiments, we designed and constructed a custom integrated circuit using a standard 0.5 mu m CMOS process for data acquisition. A sample pulse-echo signal received from the oil-air Interface (plane reflector) at 6mm had a center frequency of 11MHz with 95% fractional 6-dB bandwidth. The measured SNR of the echo was 24 dB with no averaging. B-scan image of a wire-phantom was generated to test the resolution.Yayın Annular CMUT arrays for side looking intravascular ultrasound imaging(IEEE, 2007) Zahorian, Jaime; Güldiken, Rasim Oytun; Gürün, Gökçe; Qureshi, Muhammad Shakeel; Balantekin, Müjdat; Değertekin, Fahrettin Levent; Carlier, Stephane; Şişman, Alper; Karaman, MustafaAlthough side looking intravascular ultrasound (SL-IVUS) imaging systems using single element piezoelectric transducers set the resolution standard in the assessment of the extent of coronary artery disease, improvements in transducer performance are needed to perform harmonic imaging and high resolution imaging of vulnerable plaque. With their small channel count; annular arrays exploiting the inherent broad bandwidth of CMUTs and electronic focusing capability of integrated electronics provide a path for desired SL-IVUS imaging catheters. In this paper, we first describe the design, low temperature fabrication of an 8401 mu m diameter, 8 element CMUT annular array. Testing of the individual elements in oil shows a uniform device behavior with 100% fractional bandwidth around 20MHz without including the effects of attenuation and diffraction. We also present linear scan imaging results obtained on wire targets in oil, tissue and tissue mimicking phantoms using both unfocused and dynamically focused transducers. The results for axial and lateral resolution are in agreement predicted by the simulations and show the feasibility of this approach for high resolution SL-IVUS imaging.Yayın Forward-looking IVUS imaging using an annular-ring CMUT array(IEEE, 2005) Değertekin, Fahrettin Levent; Karaman, Mustafa; Güldiken, Rasim OytunA 64-element, 1.15mm diameter annular-ring CMUT array was characterized and used for forward-looking IVUS imaging tests. The array was manufactured using low temperature processes suitable for CMOS electronics integration on a single chip. The 43×140µm2 array element has suitable view angle for forward looking imaging around 15MHz center frequency and pulse-echo measurements show nearly 100% fractional bandwidth around 17MHz. For imaging and SNR measurements, RF A-scan data sets from various targets were collected using an interconnect scheme forming a 32-element array configuration. The results demonstrate that annular-ring CMUT arrays fabricated with CMOS compatible processes are capable of forward-looking IVUS imaging.Yayın Simulated annealing based optimization of dual-ring arrays for forward-looking IVUS and ICE imaging(2010) Tekeş, Coşkun; Karaman, Mustafa; Değertekin, Fahrettin LeventForward-Looking (FL) catheter based imaging systems are highly desirable for guiding interventions in intravascular ultrasound (IVUS) and intracardiac echocardiography (ICE) applications. One of the main challenges in the array based FL-IVUS systems is the large channel count which results in increased system complexity. Synthetic phased array processing with reduced firing count simplifies the front-end and hence can enable 3-D real-time imaging. Recently, we have investigated dual-ring arrays suitable for IVUS and ICE imaging. In this study, we present two different optimized array designs based on dual circular and hexagonal rings that are suitable for synthetic phased array processing with reduced number of firings. To obtain optimal firing set that produces low side lobes in the wide-band response, we used simulated annealing algorithm. The simulated dual circular ring array has 64 Tx and 58 Rx elements, whereas the dual hexagonal ring array has 24 Tx and 126 Rx subarrays. For these two test cases, we obtained reduced sets of 512 and 256 coarray elements, and constructed 2-D PSFs at f/4 using 20-MHz, 50% FBW excitation. The simulation results show that the optimized dual circular and hexagonal ring arrays provide up to 10-dB and 5-dB improvements, respectively, in peak near side lobe level with no widening in main lobe width when compared with the full and uniformly sampled sparse coarrays.Yayın Annular-ring CMUT arrays for forward-looking IVUS: Transducer characterization and imaging(IEEE, 2006-02) Değertekin, Fahrettin Levent; Güldiken, Rasim Oytun; Karaman, MustafaIn this study, a 64-element, 1.15-mm diameter annular-ring capacitive micromachined ultrasonic transducer (CMUT) array was characterized and used for forward-looking intravascular ultrasound (IVUS) imaging tests. The array was manufactured using low-temperature processes suitable for CMOS electronics integration oil a single chip. The measured radiation pattern of a 43 X 140- mu m(2) array element depicts a 40 degrees view angle for forward-looking imaging around a 15-MHz center frequency in agreement with theoretical models. Pulse-echo measurements show a -10-dB fractional bandwidth of 104% around 17 MHz for wire targets 2.5 mm away from the array in vegetable oil. For imaging and SNR measurements, RF A-scan data sets from various targets were collected using all interconnect scheme forming a 32-element array configuration. An experimental point spread function was obtained and compared with simulated and theoretical array responses, showing good agreement. Therefore, this study demonstrates that annular-ring CMUT arrays fabricated with CMOS-compatible processes are capable of forward-looking IVUS imaging, and the developed modeling tools can be used to design improved IVUS imaging arrays.Yayın Dual electrode capacitive micromachined ultrasonic transducer array for 1-D intracardiac echocardiography (ICE)(American Society of Mechanical Engineers (ASME), 2007) Güldiken, Rasim Oytun; Zahorian, Jaime S.; Karaman, Mustafa; Değertekin, Fahrettin LeventWe designed and fabricated a 64 element 1-D linear dual electrode Capacitive Micromachined Ultrasonic Transducer (CMUT) array operating at 9.5 MHz for Intracardiac Echocardiography (ICE). The dual electrode CMUT structure increases the overall sensitivity by 12.6dB (6.2dB in receive sensitivity; 6.4dB in output pressure) when compared to optimized single electrode CMUT. We report peak output pressure of 2.3MPa on the CMUT surface when 170V AC and 180V DC is applied. This significant performance increase makes the CMUT more competitive with their piezoelectric counterparts.
